LIZNEin Gangnam, Seoul
Thoughtful care for the fine lines you notice up close. LIZNE is a tissue-restoring medical device with fish-derived polynucleotide sodium (PN). Its stated use is temporary improvement of crow’s-feet in adults. The original product contains two 1mL syringes per box. At QD Clinic, your goals and skin assessment guide the product, area and recovery plan.
Who it’s for
- Discuss fine lines at the outer eye corners, skin thickness, expression-related creases and previous injections. Muscle movement or deeper hollows may call for a different approach.
- LIZNE and Rejuran share the PN material family, but their formulations and treatment plans should be distinguished. Renefil combines HA and PN and has a different intended treatment area; these products are not interchangeable.
- At QD Clinic, your goals and skin assessment guide the product, area and recovery plan.
Suitability requires an examination. Skin thickness, health and previous procedures may make a different approach more appropriate.
How it works
LIZNE is a tissue-restoring medical device with fish-derived polynucleotide sodium (PN). Its stated use is temporary improvement of crow’s-feet in adults. The original product contains two 1mL syringes per box. LIZNE and Rejuran share the PN material family, but their formulations and treatment plans should be distinguished. Renefil combines HA and PN and has a different intended treatment area; these products are not interchangeable.
THE MECHANISM, STEP BY STEP
01The product and material
LIZNE is a tissue-restoring medical device with fish-derived polynucleotide sodium (PN). Its stated use is temporary improvement of crow’s-feet in adults. The original product contains two 1mL syringes per box.
02Your starting point
Discuss fine lines at the outer eye corners, skin thickness, expression-related creases and previous injections. Muscle movement or deeper hollows may call for a different approach.
03What sets it apart
LIZNE and Rejuran share the PN material family, but their formulations and treatment plans should be distinguished. Renefil combines HA and PN and has a different intended treatment area; these products are not interchangeable.
04Assessing the change
With PN treatment, fine lines and skin condition are reviewed after injection bumps settle. Assessment timing and further sessions follow the specific product instructions and your individual response.
Treatment areas
- Areas to assess
- Discuss fine lines at the outer eye corners, skin thickness, expression-related creases and previous injections. Muscle movement or deeper hollows may call for a different approach.
What the procedure is like
- 1Discuss the area, skin thickness, previous procedures, allergies and medicines with the doctor.
- 2Compare the product’s intended use, realistic goals, limitations and total cost.
- 3After appropriate comfort measures and cleansing, the doctor treats the agreed areas.
- 4Receive aftercare and contact instructions, and arrange an appropriate review.
Appointment length depends on consultation, numbing and treatment extent. Tell us your available time and important plans when booking.
Recovery & aftercare
- Injection marks, redness, swelling, bruising, tenderness or temporary bumps can occur; recovery varies.
- Avoid strong irritation, overheating and strenuous exercise while the skin settles. Follow your instructions for washing and makeup.
- Massage and pressure advice differs by product. Follow your clinician’s instructions rather than another product’s routine.
What to expect over time
A general guide to how the days and months after treatment usually unfold. Results vary by individual.
Immediately
Initial swelling and fullness are not the final result.
Early recovery
Monitor bruising, swelling and injection marks. Contact the clinic if symptoms worsen or persist.
Review LIZNE
With PN treatment, fine lines and skin condition are reviewed after injection bumps settle. Assessment timing and further sessions follow the specific product instructions and your individual response. Compare photographs taken under consistent conditions and findings at review.
Next steps
Plan any further session only after assessing the response and recovery.
Sessions & results
Session count and spacing depend on examination, the specific product instructions and your response. Allow recovery time before an important event or journey.
How it compares
LIZNE and Rejuran share the PN material family, but their formulations and treatment plans should be distinguished. Renefil combines HA and PN and has a different intended treatment area; these products are not interchangeable.
| Comparison | LIZNE | Renefil |
|---|---|---|
| Material | PN | HA + PN |
| Selection | Discuss fine lines at the outer eye corners, skin thickness, expression-related creases and previous injections. Muscle movement or deeper hollows may call for a different approach. | The doctor assesses fold depth, volume loss and surrounding support before deciding what needs correction. |
| Progress | With PN treatment, fine lines and skin condition are reviewed after injection bumps settle. Assessment timing and further sessions follow the specific product instructions and your individual response. | With HA products, lines, hydration and surface quality are assessed after swelling settles. The area and formulation influence the course and duration. |
Neither is “better” — they work differently and suit different goals. The right choice is decided after we assess your skin.
Safety & considerations
Possible reactions
- Infection, persistent nodules, unevenness, inflammation or allergic reactions can occur.
- Injections carry rare but serious risks including vascular injury or blockage and tissue damage.
When to take extra care
- Disclose pregnancy or breastfeeding, allergies, immune conditions, medicines, previous fillers and threads.
- Active inflammation or infection at the site needs assessment before treatment is scheduled.
Worsening pain, pale or mottled skin, visual symptoms or breathing difficulty need urgent medical attention. Outcomes and duration vary; a specific result is not guaranteed.
Your care at QD Clinic
Start with the concern
Distinguish dryness, wrinkles, volume loss and laxity before setting priorities.
Understand your product
Review the product, presentation, proposed amount and overall cost.
Plan through recovery
Build follow-up and aftercare around important plans and your ability to return.
Pricing
Cost depends on the product, presentation, amount, treatment area and any accompanying care. Confirm the total and what is included during consultation.
Frequently asked questions
LIZNE is a tissue-restoring medical device with fish-derived polynucleotide sodium (PN). Its stated use is temporary improvement of crow’s-feet in adults. The original product contains two 1mL syringes per box.
LIZNE and Rejuran share the PN material family, but their formulations and treatment plans should be distinguished. Renefil combines HA and PN and has a different intended treatment area; these products are not interchangeable.
With PN treatment, fine lines and skin condition are reviewed after injection bumps settle. Assessment timing and further sessions follow the specific product instructions and your individual response.
Session count and spacing depend on examination, the specific product instructions and your response. Allow recovery time before an important event or journey.
Stinging or pressure may occur. Discuss comfort measures suited to the area, formulation and your sensitivity; treatment is not guaranteed to be painless or swelling-free.
Injection marks, redness, swelling, bruising, tenderness or temporary bumps can occur; recovery varies. Avoid strong irritation, overheating and strenuous exercise while the skin settles. Follow your instructions for washing and makeup. Massage and pressure advice differs by product. Follow your clinician’s instructions rather than another product’s routine.
Cost depends on the product, presentation, amount, treatment area and any accompanying care. Confirm the total and what is included during consultation.
Disclose pregnancy or breastfeeding, allergies, immune conditions, medicines, previous fillers and threads. Active inflammation or infection at the site needs assessment before treatment is scheduled.
Often considered together
Treatments that are sometimes planned alongside this one, decided at consultation.
+Medical assessment
Discuss fine lines at the outer eye corners, skin thickness, expression-related creases and previous injections. Muscle movement or deeper hollows may call for a different approach. Suitability requires an examination. Skin thickness, health and previous procedures may make a different approach more appropriate.
For international patients
Consultation in English / 中文 / 日本語 · WhatsApp · WeChat · KakaoTalk · a 4-minute walk from Sinnonhyeon / Nonhyeon Station (hours in KST) · card payment.
For International Patients